We have successfully used the ATMS dynamic culture system in order to test mechanosensitivity of a G protein coupled receptor. The device is straight forward to use and allows to test a range of different experimental approaches. Cells can be stretched and unstretched to measure on and off responses, they can be stretched to different extents for variable periods of time, and they can be exposed to repeated mechanical stresses and stress cycles. The stretchable membranes are very straight forward to use and we have never had any issues with cells not attaching or dying. I recommend this system highly.

“Differentiation of pluripotent stem cells into cardiomyocytes has been well established but cell maturity is often a concern. We have been using the EX1D stretcher to assess how dynamic stretch impacts stem cell maturation. The stretcher system provides significant experimental flexibility with many attachments for different culture types and models. This has allowed us to use the stretcher basically right out of the box!”

The Taihoya ATMS EX-1 is a turn-key system with a well thought-out design that is easy to set up and calibrate.  The system is versatile, flexible, and user-friendly.  The EX-1 has an array of offset sized cam displacements with simple drop-in for easy setting of stretch and compression percentages with excellent repeatability.  The documentation manual of the instrument has sections corresponding to each of the attachments with a step-by-step layout for easy setup. It is an excellent instrument for biomechanical studies on the quantitative and dynamic effects of stretch and compression on biological tissues.