We have successfully used the ATMS dynamic culture system in order to test mechanosensitivity of a G protein coupled receptor. The device is straight forward to use and allows to test a range of different experimental approaches. Cells can be stretched and unstretched to measure on and off responses, they can be stretched to different extents for variable periods of time, and they can be exposed to repeated mechanical stresses and stress cycles. The stretchable membranes are very straight forward to use and we have never had any issues with cells not attaching or dying. I recommend this system highly.